Prevalence and Genotyping of Human Papillomavirus among Women in the Departments of Niari and Bouenza, Republic of the Congo

Human papillomaviruses (HPV) are at the origin of many mucosal, benign or malignant skin pathologies. Some so-called high-risk genotypes, especially types 16 and 18, involved in genesis cervical cancer, one most common cancers women. To determine prevalence HPV infections to identify oncogenic genotypes circulating departments Niari Bouenza. A total 207 samples collected between 2019 2020 were studied. Cervico vaginal smears performed on all for cytological analysis, DNA detection genotyping GeneXpert. The average age women who participated this study was 43.67 ± 12.31 years 38.29 10.52 Bouenza with intervals ranging from 18 80 years. Cytological analysis these reported following prevalences: Normal diagnosed 89.58% (186/207) cases, ASCUS 5.31% (11/207) LSIL 2.89% (6/207) ICC 1.93% (4/207) cases. infection detected 83.54% (66/186) without lesions, 6.32% (5/11) 10.12% (8/10) abnormalities [5.06% (4/6) LSIL, 5.06% (4/4) ICC]. In total, 79 our tested positive more HPV-HR types, 38.16%. department 37.5% (48/128) HPV, 39.24% (31/79) HPV. Multiple ranged two than three strains No statistically significant association observed socio-demographic characteristics (p > 0.05). On other hand, varied significantly according cytology = 0.001). results obtained show predominance Congo.